Erratum to ‘‘Multimodal imaging of residual function and compensatory resource allocation in cortical atrophy: a case study of parietal lobe function in a patient with Huntington’s disease’’

Ž . In a case of Huntington’s disease HD with dementia and pronounced parieto-frontal atrophy, the functional state Ž . of the affected regions was investigated using functional magnetic resonance imaging fMRI and fluorodeoxygluŽ . cose-positron emission tomography FDG-PET . It was observed that although parietal areas showed extensive atrophy and reduced resting glucose metabolism, the patient performed with similar accuracy but with longer response time in a visuospatial task compared with healthy control subjects. At the same time, the blood oxygen Ž . level-dependent BOLD fMRI signal in these areas, which are involved in visuospatial processing, showed a similar Ž . task-dependent modulation as in control subjects. The signal amplitude signal percent change of the task-dependent activation was even higher for the HD patient than in the control group. This residual functionality of parietal areas involved in visuospatial processing could account for the patient’s performance in the task concerned, which contrasted with his poor performance in other cognitive tasks. The increased percent-signal change suggests that a U Corresponding author, Clinical Neurophysiology, Department of Psychiatry and Psychotherapy I, University of FrankfurtrMain, Heinrich-Hoffmann-Str. 10, D-60528 Frankfurt, Germany. Tel.: q49 69 6301 5897; fax: q49 69 6301 5189; e-mail: [email protected]